Source: Bio-Rad Laboratories, Inc.
Wednesday, October 29, 2008
Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb), a multinational manufacturer and distributor of life science research and clinical diagnostic products, announced today the availability of a technical note (tech note 5761), which describes in detail a new RNA quality indicator (RQI) available with Bio-Rad’s Experion™ automated electrophoresis system.
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Entitled “Development and Validation of RQI: An RNA Quality Indicator for the Experion Automated Electrophoresis System”, the technical note introduces RQI as a method to standardize and quantitate RNA integrity. A specialized algorithm compares three regions of an electrophoretic profile of RNA samples to a series of standardized degraded RNA samples. The RQI method returns a number between 10 (intact RNA) and one (highly degraded RNA) for each eukaryotic RNA sample run on an Experion RNA StdSens or HighSens analysis chip. It gives a consistent evaluation of RNA quality and is a convenient quantifier in determining the extent of degradation of RNA samples. Easy to use, even for an inexperienced operator, the RQI feature and Experion software displays the RNA integrity data in a convenient “Run Summary” page.
The simple concept behind the RQI gives results that are comparable to RIN, another method for checking integrity. It works well over a wide range of RNA concentrations (100 pg to 5,000 ng), is very reproducible (%CV <3), and is applicable to a wide range of mammalian tissues. With the new software, researchers can quantitatively assess the integrity of their RNA samples before embarking on labor-intensive and costly projects.
Availability
The technical note (tech note 5761) is available either from a local Bio-Rad sales office or it can be requested by visiting the Bio-Rad website at www.bio-rad.com. To obtain a copy, type the technical note title or 5761 into the search box located at the top-right of the home page.
About Bio-Rad
Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb) has remained at the center of scientific discovery for more than 50 years manufacturing and distributing a broad range of products for the life science research and clinical diagnostic markets. The company is renowned worldwide among hospitals, universities, major research institutions, as well as biotechnology and pharmaceutical companies for its commitment to quality and customer service. Founded in 1952, Bio-Rad is headquartered in Hercules, California, and serves more than 85,000 research and industry customers worldwide through its global network of operations. The company employs approximately 6,300 people globally and had revenues approaching $1.5 billion in 2007. For more information, visit www.bio-rad.com.
NOTE TO THE EDITOR:
Information in this release applies specifically to products available in the United States. Product availability and specifications may vary in non‑U.S. markets.
If you choose to review this item, your readers will receive the quickest response to their inquiries by e‑mailing them to lsg.orders.us@bio-rad.com or by calling 1-800-424-6723.
For more information contact:
Mary Grace Brubacher
Bio-Rad Laboratories, Inc.
510-741-5347
MaryGrace_Brubacher@bio-rad.com